ㄇㄧㄥˋmìngㄊㄨˊㄎㄢˇkǎnㄎㄜˇ

  1. 命運不順一生真是命途坎坷。」偃蹇困窮平步青雲飛黃騰達

to have a tough life, to meet much adversity in one's life